The brand was created by José "Pepin" Garcia as well as the co-founders of United Tobacco Erik Espinosa & Eddie Ortega all 601 cigars are manufactured at the Tabacalera Cubana factory in the Estelí, Nicaragua. The brand was introduced in August 2006.

United Tobacco's latest creation, Cubao is also manufactured by Don 'Pepin' Garcia in Esteli, Nicaragua.

The 601 Maduro (blue label) was given Robb Reports 'Best of the best' for 2008. It also received a 91 rating in Cigar Aficionado's Cigar Insider publication.

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